Implication Of Covid-19 Infection On PRP Extraction In A Patient Suffering From Knee Osteoarthritis

Background: Knee osteoarthritis (KOA) is one of the most prevalent degenerative diseases that cause pain and disability. None of the currently available treatments reverses or heals the degenerative nature of this condition. There were many research studies on the efficacy of PRP therapy in early KOA patients. However, there was no clinical study on its extraction or administration in a COVID-19 patient with KOA.Hence, the main objective of this observational study was to analyse the implication of COVID-19 infection on PRP extraction along with Red Blood Cell Distribution Width (RDW) and platelet count levels.

Methods: We present a case report of knee osteoarthritis administered with two ultrasound-guided Platelet-Rich Plasma (PRP) injections pre and post covid-19 infection.

As the patient was affected with COVID-19 infection immediately after a week of the first PRP session, he was finally administered the second dose only after 21 days, followed by the third final dose after 6 weeks.

Conclusion: As COVID-19 infection affects the lungs, there was an increase in hematocrit values, leading to difficulty in plasma separation. Furthermore, there was an elevated level of RDW with the change in platelet count.