Publication - 5
Safety and Efficacy of BMAC and Adipose-Derived MSCs Treatment in Combination for Knee Osteoarthritis
Journal Name: American Journal of Surgery and Clinical Case Reports
Background: : Knee osteoarthritis (KOA) is one of the most widespread degenerative diseases that lead to pain and disability. Oral NSAIDs and Intra-articular corticosteroid injections are usually used to relieve symptoms in patients with knee osteoarthritis. In this study, we assessed the safety and efficacy of the combination of autologous adipose-derived mesenchymal stem cells (ADMSC) that is mechanically treated with a stromal vascular fraction (SVF) and bone marrow aspirate concentrate (BMAC) injections on pain reduction and improvement of functioning in patients with KOA. The aim was to gain more information as there is a lack of research on combinational orthobiologic treatment.
Methods: 302 knee joints of patients aged between 40 and 85 years with KOA, grade 3-4 of the Kellgren–Lawrence scale were administered with a single intra-articular injection of BMAC+ADMSC combination. These patients were evaluated before and 12 months after BMAC +AD-MSC treatment using the Visual Analog Scale (VAS) and Oxford Knee Score (OKS).
Results: After 12 months of follow-up, both VAS and OKS scores improved significantly in the BMAC +AD-MSC group from baseline after the injection (P < 0.05). No acute pain flares, infections, or other adverse complications were reported during this period.
Conclusion: A combination of BMC and AD-MSC was safe and effective in improving patient reported outcomes in patients with moderate-to severe KOA for the entire duration of 12 months.
THE EFFECT OF PLATELET-RICH PLASMA THERAPY ON THE ROTATOR CUFF TENDINOPATHY
Publication – 1 REVIEW ARTICLE Journal Name: International Journal of …
BONE MARROW ASPIRATE CONCENTRATE AND ADIPOSE-DERIVED MSCS TREATMENT FOR KNEE OSTEOARTHRITIS: A SYSTEMATIC REVIEW
Publication – 2 RESEARCH ARTICLE BMAC and Adipose-Derived MSCs Treatment …
EFFECT OF PRP THERAPY IN CONJUNCTION WITH PHYSICAL THERAPY FOR ROTATOR CUFF TENDINOPATHY
Publication – 3 CASE REPORT Journal Name: International Journal of Clinical Rheumatology …
EFFICACY AND SAFETY OF REGENERATIVE TREATMENT IN KNEE OSTEOARTHRITIS PATIENTS AFTER COVID-19 VACCINATION
Publication – 4 RESEARCH ARTICLE Efficacy and Safety of Regenerative …